New Antidepressant Agent with Approval

Vortioxetine, an agent with antagonistic and agonistic serotonergic activity in rats data ( has been approved by the FDA for treatment of major depressive disorder in the U.S.  ( and also the Committee for Medicinal Products for Human Use gave a marketing authorization for the European market (
Clinical trials showed a superior effect on depressive symptoms of vortioxetine in comparison to placebo (e.g. or as well as a lack of difference between vortioxetine and placebo (e.g. or

Vortioxetine has been reported to have positive effects on cognition ( and did further not impair psychomotor reaction e.g. during driving in comparison to mirtazapine (

Interestingly, vortioxetine administration in the rat was paralleled by an increase of EEG power while administration of escitalopram and duloxetine were not (

Since there are currently no studies avalable thatstudied EEG alterations in humans  associated with vortioxetine, further research should use electrophysiological methods to shed more light on the mode of action of this new agent.

Posted on 6 jan 2014


EEG research and Corona Crisis 2020

Many EEG researchers are not able to perform assessment of EEG recordings in their labs due to the pandemic Covid-19 crisis. Arnaud Delorme and Scott Makeig, heads of the EEGlab platform, propose several things to do dring these hard times to prevent the lockdown of EEG research Read their hints here.

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Abstract Book available

 The complete Abstract Book for the Zurich 2018 Meeting is available now

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Final Program

The final program for the IPEG Meeting November 21st-25th in Zurich is ready for download HERE

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