Resting-state connectivity biomarkers define neurophysiological subtypes of depression

A recently published study defined novel subtypes of depression that transcend current diagnostic boundaries and may be useful for predicting therapeutic responsiveness. They show by using functional magnetic resonance imaging (fMRI) in a large multisite sample (n = 1,188), that patients with depression can be subdivided into four neurophysiological subtypes ('biotypes') defined by distinct patterns of dysfunctional connectivity in limbic and frontostriatal networks. Clustering patients on this basis enabled the development of diagnostic classifiers (biomarkers) with high (82–93%) sensitivity and specificity for depression subtypes in multisite validation (n = 711) and out-of-sample replication (n = 477) data sets. Read more


Posted on 16 dec 2016

News



Abstract Book available

 The complete Abstract Book for the Zurich 2018 Meeting is available now

...
Read more

Final Program

The final program for the IPEG Meeting November 21st-25th in Zurich is ready for download HERE

...
Read more

Preliminary Programm ZURICH IPEG Meeting 2018

Preliminary Program of 2018 IPEG Meeting is available now!

See here

or download here

...
Read more